Originally a chapel under the parish of Calumpit,it became a church in 1731 with Fr. Juan Albarran,an Augustinian as the first curate. It was rebuilt in 1871 by Fr. Ignacio Manzanares. The church was taken over by the Filipino clergy in 1896 with Fr. Clemente Garcia as the first Filipino curate. He was succeeded by Fr. Dr. Mariono Sevilla from 1902-1922,Fr. Exequiel Morales,1922-1936. Fr. Celestino Rodriguez,curate since 1936 improved the church assisted by the Congregation of the Religiosas de la Virgen Maria (R.V.M.). It was made into a national shrine to honor the mother of the Blessed Virgin,St. Anne. This is the only place in the country where the relics of Sts. Anne and Joaquin,parents of the Blessed Virgin Mary,are venerated.

How to get there:
All buses bound for the northern parts of Luzon pass through Bulacan.